Endocrine Abstracts

Introduction: Although in-vitro models suggest GH-induced differentiation, migration and survival of astrocytes and oligodendrocytes, no studies had been published in-vivo. We want to evaluate the efficacy and safety of GH associated with physical therapy compared to placebo in patients with complete spine injury (SI) and associated GH deficiency (GHD).Methods: Eighteen Patients with complete SI were screened for GHD (glucagon test). 12 severe (...

Objectives: To assess baseline differences on lipid profile in individuals with gender identity disorder (male to female, M2F and female to male, F2M) in relation to prior cross-sex hormone treatment (CHT) or not, and changes in the lipid profile after 24 months of treatment and follow-up in our unit.Methods: Transversal study by revision of medical records of 235 patients visited for first time in our service from 2006 to 2010. Clinical and analytical r...

Introduction: Previous studies indicate a high prevalence of HIV infection in the transgender population and associate it with sexual risk behavior, psychiatrical and socio-economic problems. Anyway, few data are available regarding other factors. We assessed the prevalence of HIV and other associated characteristics in a transgender population of Catalonia.Methods: Cross-sectional study including 234 transsexuals that started follow-up in a reference ce...

Introduction: Waist circumference is a validated tool to measure obesity-associated cardiovascular risk factor. However it does not differentiate between superficial and visceral abdominal fat. Ultrasonography has many advantages over TC/DEXA in abdominal fat assessment, specially imaging pre-peritoneal, omental and retroperitoneal fat. Our aims were to validate the diagnostic technique and to observe correlations between different abdominal fat layers with clinical and analyt...

Introduction: Transsphenoidal surgery (TSS) is the procedure of choice in Cushing disease (CD), with immediate post-operative remission rates ranging between 59 and 94% and recurrence rates between 3 and 46%, both depending upon the definition criteria and the duration of the follow-up. Our aim was to assess the rate of remission, recurrence and persistence of the disease after the first treatment and to identify predictors of remission in the CD population of our center durin...